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Objectives:Identify the mechanism of action of fresh frozen plasma.Describe the adverse effects of fresh frozen plasma.Review the appropriate monitoring of patients who are administered fresh frozen plasma.Explain some interprofessional team strategies to improve care coordination and advance managing conditions treated with fresh frozen plasma.Access free multiple choice questions on this topic.
Fresh frozen plasma is the fluid portion of a unit of whole blood frozen in a designated time frame, usually within 8 hours. Fresh frozen plasma contains all coagulation factors except platelets. Fresh frozen plasma contains fibrinogen (400 to 900 mg/unit), albumin, protein C, protein S, antithrombin, tissue factor pathway inhibitor. It is free of erythrocytes and leukocytes. Fresh frozen plasma corrects coagulopathy by replacing or supplying plasma proteins in patients who are deficient in or have defective plasma proteins. A standard dose of 10 to 20 mL/kg (4 to 6 units in adults) will raise factor levels by approximately 20%. An increase of roughly 10% of several factors is enough to bring about hemostasis. Also, fresh frozen plasma provides some volume resuscitation, as each unit contains approximately 250 ml.[4][5][6][7]
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The Tilka Manjhi Bhagalpur University, also known as Bhagalpur University, is a premier institution for providing higher education in the state of Bihar. The university is situated in Bhagalpur town of Bihar State in India and is named after famous freedom fighter Tilka Manjhi. Established on 12 July 1960, it is a public university sprawled within 264 acres of lush green campus ideal for teaching and learning. The university has 6 Faculties, 34 Teaching Departments, 5 Research Centres and 12 Constituent Colleges, besides affiliated to it 11 Colleges and 14 B.Ed. Colleges. 153554b96e
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