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The database was comprised of patients from the following cities: Camocim, Capitão, Catanduva, Ceará, Cachoeira do Sul, Cercadura, César, Cunha, Dom Pedrito, Espinhaço, Franca, Ipatinga, Itajaí, Jau, Lages, Lindóia, Londrina, Mariana, Messejana, Montes Claros, Mucuri, Nova Juventude, Petrolina, Piripiri, Santa Terezinha, São Vicente, Seropédica and Tubarão. The patients were traced to the database by searching through the records that were created during their hospitalization, using the following information: age, sex, area of residence, HIV-1 infection serological test, date of diagnosis of HIV-1 infection, HIV-1 viral load and serial count of T CD4+ lymphocytes. The data collected were analyzed by using the Epi Info 6.0 (Centers for Disease Control and Prevention, USA) and SPSS software, version 12.0. ( IBM ). Categorical variables are presented as proportions and were analyzed by the Chi-square test and Fisher exact test. The significance level was set at 5% (P = 0.05).

In addition, in our study, a significant association was observed between the frequency of OIs and the serial count of T CD4+ lymphocytes in patients who were not treated with HAART (P = 0.0007).

The Zodiac Killer also referred to himself as the Zodiac,[n 5] a crime that he would commit for four years.[n 6] Although he never stated his real identity to the police, the behavior and the occupation of the killer was so detailed that he was known to many as the Zodiac Killer. He was accused by the police of committing at least 32 murders and 12 rapes, which included the murder of the young couple in San Francisco in April, 1968. The Zodiac often sent letters to the police, newspapers, and private individuals with riddles and cryptograms. He called himself the Zodiac because it rhymed with Mothman, a recurring figure in local folklore.

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